Endothelium-dependent relaxation of rat aorta induced by resveratrol

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Saffron Induced Relaxation in Isolated Rat Aorta via Endothelium Dependent and Independent Mechanisms

Crocus sativus L. (saffron) is a widely used food additive for its color and taste. The hypotensive effects of saffron have been shown in previous studies. The aim of this study was to evaluate the mechanism of vasodilatory effects induced by saffron on isolated rat aorta.To study the vasodilatory effects of saffron aqueous extract (0.5, 1 and 2 mg/mL), isolated rat thoracic aorta rings were co...

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Saffron Induced Relaxation in Isolated Rat Aorta via Endothelium Dependent and Independent Mechanisms

Crocus sativus L. (saffron) is a widely used food additive for its color and taste. The hypotensive effects of saffron have been shown in previous studies. The aim of this study was to evaluate the mechanism of vasodilatory effects induced by saffron on isolated rat aorta.To study the vasodilatory effects of saffron aqueous extract (0.5, 1 and 2 mg/mL), isolated rat thoracic aorta rings were co...

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Endothelium-dependent relaxation in aorta of BB rat.

The study was undertaken to determine whether the phenomenon of endothelium-dependent relaxation was impaired in the spontaneously diabetic BB Wistar rat. Endothelium-dependent relaxation in the aorta of overtly diabetic animals was compared with that in nondiabetic BB rats. The relaxative responses were elicited in vitro to acetylcholine (-8.0 to -5.5 log M) and histamine (-7.0 to -3.0 log M) ...

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Endothelium-dependent and-independent relaxation induced by resveratrol in rat superior mesenteric arteries.

Resveratrol (Res) is a specific agonist of sirtuin 1, and has many cardioprotective effects. Although Res is able to relax various vascular beds, its pharmacological properties in rat superior mesenteric arteries and the underlying mechanism are not well clarified. The aim of present study was to investigate the vasorelaxant effects of Res on rat superior mesenteric arteries and the mechanisms ...

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Nitric oxide mediated endothelium-dependent relaxation induced by glibenclamide in rat isolated aorta.

OBJECTIVES Glibenclamide was found to act as both a selective ATP-sensitive K(+) channel blocker and a vasorelaxant. The exact mechanisms underlying the relaxant effect of glibenclamide are unknown. The present study was designed to examine the role of endothelium/nitric oxide in glibenclamide-induced relaxation in rat isolated aortic rings. METHODS A combination of experimental approaches in...

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ژورنال

عنوان ژورنال: Acta veterinaria

سال: 2007

ISSN: 0567-8315

DOI: 10.2298/avb0703123g